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Dosage / Direction for Use

Dosage: Oral route.

The dose is one tablet of trimetazidine 35 mg twice daily, i.e. once in the morning and once in the evening, during meals.

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Elderly patients: Elderly patients may have increased trimetazidine exposure due to age-related decrease in renal function. In patients with moderate renal impairment (creatinine clearance [30-60] ml/min), the recommended dose is 1 tablet of 35mg in the morning during breakfast.

Dose titration in elderly patients should be exercised with caution.

Paediatric population: The safety and efficacy of trimetazidine in children aged below 18 years have not been established. No data are available.

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